What the FDA labels say about taking them together
Nelfinavir and umeclidinium/vilanterol
Umeclidinium/vilanterol's FDA label of June 2, 2023 names nelfinavir in its warnings and precautions section; the nelfinavir label PlainMeds reads does not name umeclidinium/vilanterol. The umeclidinium/vilanterol label: “Interactions with Strong Cytochrome P450 3A4 Inhibitors Caution should be exercised when considering the coadministration of ANORO ELLIPTA with ketoconazole and other known strong cytochrome P450 3A4 (CYP3A4) inhibitors …”
Check it at the source: the nelfinavir FDA label on DailyMed (effective December 11, 2025, AGOURON); the umeclidinium/vilanterol FDA label on DailyMed (effective June 2, 2023, GlaxoSmithKline LLC).
What does the nelfinavir label say about umeclidinium/vilanterol?
Nelfinavir's label (effective December 11, 2025) does not name umeclidinium/vilanterol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (VIRACEPT), AGOURON, effective December 11, 2025 (SPL set e72c2bc6-9462-4a2e-8e1d-b97592376cbd), via openFDA; the full label on DailyMed
What does the umeclidinium/vilanterol label say about nelfinavir?
Umeclidinium/vilanterol label, warnings and precautionsInteractions with Strong Cytochrome P450 3A4 Inhibitors Caution should be exercised when considering the coadministration of ANORO ELLIPTA with ketoconazole and other known strong cytochrome P450 3A4 (CYP3A4) inhibitors (including, but not limited to, ritonavir, clarithromycin, conivaptan, indinavir, itraconazole, lopinavir, nefazodone, nelfinavir, saquinavir, telithromycin, troleandomycin, voriconazole) because increased cardiovascular adverse effects may occur [see Drug Interactions ( 7.1 ), Clinical Pharmacology ( 12.3 )].
Source: FDA drug label (Anoro Ellipta), GlaxoSmithKline LLC, effective June 2, 2023 (SPL set 2dbd0671-c565-40c5-bf0f-e324db26799c), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Nelfinavir | Umeclidinium/vilanterol | |
|---|---|---|
| Labeled for | HIV | COPD |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $4.95 per inhaler 62.5-25 mcg inhaler |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once