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What the FDA labels say about taking them together

Nelfinavir and saxagliptin

Saxagliptin's FDA label of January 27, 2026 names nelfinavir in its drug interactions section; the nelfinavir label PlainMeds reads does not name saxagliptin. The saxagliptin label: “Similar significant increases in plasma concentrations of saxagliptin are anticipated with other strong CYP3A4/5 inhibitors.”

Check it at the source: the nelfinavir FDA label on DailyMed (effective December 11, 2025, AGOURON); the saxagliptin FDA label on DailyMed (effective January 27, 2026, Glenmark Pharmaceuticals Inc., USA).

What does the nelfinavir label say about saxagliptin?

Nelfinavir's label (effective December 11, 2025) does not name saxagliptin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (VIRACEPT), AGOURON, effective December 11, 2025 (SPL set e72c2bc6-9462-4a2e-8e1d-b97592376cbd), via openFDA; the full label on DailyMed

What does the saxagliptin label say about nelfinavir?

Saxagliptin label, drug interactions

Similar significant increases in plasma concentrations of saxagliptin are anticipated with other strong CYP3A4/5 inhibitors (e.g., atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin).

Source: FDA drug label (SAXAGLIPTIN), Glenmark Pharmaceuticals Inc., USA, effective January 27, 2026 (SPL set e286ffd4-c598-47fb-af06-2e15f7e6f99f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Nelfinavir generic labelers
3Saxagliptin generic labelers
NelfinavirSaxagliptin
Labeled forHIVType 2 diabetes
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$1.04 per tablet 5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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