What the FDA labels say about taking them together
Nelfinavir and ritonavir
Nelfinavir's FDA label of December 11, 2025 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name nelfinavir. The nelfinavir label: “Concentrations of nelfinavir were increased when coadministered with ritonavir. An appropriate dose of nelfinavir for this combination, with respect to safety and efficacy, has not been established.”
Check it at the source: the nelfinavir FDA label on DailyMed (effective December 11, 2025, AGOURON); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the nelfinavir label say about ritonavir?
Nelfinavir label, drug interactionsConcomitant Drug Class/Drug Name: Ritonavir; Effect on Concentration: ↑ nelfinavir ↔ ritonavir; Clinical Comment: Concentrations of nelfinavir were increased when coadministered with ritonavir. An appropriate dose of nelfinavir for this combination, with respect to safety and efficacy, has not been established.
Source: FDA drug label (VIRACEPT), AGOURON, effective December 11, 2025 (SPL set e72c2bc6-9462-4a2e-8e1d-b97592376cbd), via openFDA; the full label on DailyMed
What does the ritonavir label say about nelfinavir?
Ritonavir's label (effective July 23, 2026) does not name nelfinavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Nelfinavir | Ritonavir | |
|---|---|---|
| Labeled for | HIV | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once