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What the FDA labels say about taking them together

Nelfinavir and quetiapine

Nelfinavir's FDA label of December 11, 2025 names quetiapine in its drug interactions section; the quetiapine labels PlainMeds reads (2) do not name nelfinavir. The nelfinavir label: “Consider alternative antiretroviral therapy to avoid increases in quetiapine drug exposures.”

Check it at the source: the nelfinavir FDA label on DailyMed (effective December 11, 2025, AGOURON); the quetiapine FDA label on DailyMed (effective April 10, 2026, H2-Pharma, LLC).

What does the nelfinavir label say about quetiapine?

Nelfinavir label, drug interactions

Consider alternative antiretroviral therapy to avoid increases in quetiapine drug exposures.

Source: FDA drug label (VIRACEPT), AGOURON, effective December 11, 2025 (SPL set e72c2bc6-9462-4a2e-8e1d-b97592376cbd), via openFDA; the full label on DailyMed

What does the quetiapine label say about nelfinavir?

Quetiapine's label (effective April 10, 2026) and its 1 other brand-application label do not name nelfinavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (SEROQUEL), NDA020639 (Cheplapharm), as published by H2-Pharma, LLC, effective April 10, 2026 (SPL set 8ae62aaf-f8c5-417f-baac-0098369ca322), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Nelfinavir generic labelers
48Quetiapine generic labelers
NelfinavirQuetiapine
Labeled forHIVSchizophrenia, Bipolar disorder, Depression
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.127 per tablet 300 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?