What the FDA labels say about taking them together
Nelfinavir and nevirapine
Nelfinavir's FDA label of December 11, 2025 names nevirapine in its drug interactions section, and nevirapine's label names nelfinavir too. The nelfinavir label: “Concentrations of nelfinavir were decreased when coadministered with nevirapine. An appropriate dose of nelfinavir with respect to safety and efficacy has not been established.”
Check it at the source: the nelfinavir FDA label on DailyMed (effective December 11, 2025, AGOURON); the nevirapine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.).
What does the nelfinavir label say about nevirapine?
Nelfinavir label, drug interactionsConcomitant Drug Class/Drug Name: Nevirapine; Effect on Concentration: ↓ nelfinavir (C min); Clinical Comment: Concentrations of nelfinavir were decreased when coadministered with nevirapine. An appropriate dose of nelfinavir with respect to safety and efficacy has not been established.
Source: FDA drug label (VIRACEPT), AGOURON, effective December 11, 2025 (SPL set e72c2bc6-9462-4a2e-8e1d-b97592376cbd), via openFDA; the full label on DailyMed
What does the nevirapine label say about nelfinavir?
Nevirapine label, drug interactionsDrug Name: Nelfinavir; Effect on Concentration of Nevirapine or Concomitant Drug: ↓ Nelfinavir M8 Metabolite ↓ Nelfinavir C min; Clinical Comment: The appropriate doses of the combination of nevirapine and nelfinavir with respect to safety and efficacy have not been established.
Source: FDA drug label (Nevirapine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set c6e93829-7024-48f6-8023-da6ff27dfc0a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Nelfinavir | Nevirapine | |
|---|---|---|
| Labeled for | HIV | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.147 per tablet 200 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once