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What the FDA labels say about taking them together

Multiple vitamins and warfarin

Multiple vitamins's FDA label of November 20, 2024 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name multiple vitamins. The multiple vitamins label: “Decreased Anticoagulant Effect of Warfarin: Interferes with Megaloblastic Anemia Diagnosis: Avoid during testing for this disorder”

Check it at the source: the multiple vitamins FDA label on DailyMed (effective November 20, 2024); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the multiple vitamins label say about warfarin?

Multiple vitamins label, drug interactions

In patients who are co-administered warfarin and INFUVITE PEDIATRIC, blood levels of prothrombin/INR should be monitored to determine if dose of warfarin needs to be adjusted [see Warnings and Precautions ( 5.4 )].

Multiple vitamins label, warnings and precautions

Decreased Anticoagulant Effect of Warfarin: Interferes with Megaloblastic Anemia Diagnosis: Avoid during testing for this disorder

Source: FDA drug label (Infuvite Adult, NDA021163), Sandoz Inc, effective November 6, 2024 (SPL set 14c7bfc5-07e8-400f-b8ff-5e4794dd2805), via openFDA

Source: FDA drug label (Infuvite Pediatric), Sandoz Inc, effective November 20, 2024 (SPL set 6d06546e-8b0a-4490-82d9-397bd902a044), via openFDA; the full label on DailyMed

What does the warfarin label say about multiple vitamins?

Warfarin's label (effective May 29, 2026) does not name multiple vitamins in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Multiple vitamins generic labelers
19Warfarin generic labelers
Multiple vitaminsWarfarin
Labeled forn/aBlood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?