What the FDA labels say about taking them together
Mirtazapine and warfarin
Mirtazapine's FDA label of August 6, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name mirtazapine. The mirtazapine label: “Clinical Impact; The concomitant use of warfarin with REMERON/REMERONSolTab may result in an increase in INR.”
Check it at the source: the mirtazapine FDA label on DailyMed (effective August 6, 2025, Organon LLC); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the mirtazapine label say about warfarin?
Mirtazapine label, drug interactionsClinical Impact; The concomitant use of warfarin with REMERON/REMERONSolTab may result in an increase in INR [see ].
Source: FDA drug label (REMERON), Organon LLC, effective August 6, 2025 (SPL set 98ad1917-a094-44f5-a28f-a64a8cfcd887), via openFDA; the full label on DailyMed
What does the warfarin label say about mirtazapine?
Warfarin's label (effective May 29, 2026) does not name mirtazapine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Mirtazapine | Warfarin | |
|---|---|---|
| Labeled for | Depression | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.063 per tablet 15 mg tablet | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once