What the FDA labels say about taking them together
Meclofenamate and warfarin
Meclofenamate's FDA label of April 15, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name meclofenamate. The meclofenamate label: “Warfarin The effects of warfarin and NSAIDs on GI bleeding are synergistic, such that users of both drugs together have a risk of serious GI bleeding higher than users of either drug alone.”
Check it at the source: the meclofenamate FDA label on DailyMed (effective April 15, 2026, Mylan Pharmaceuticals Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).
What does the meclofenamate label say about warfarin?
Meclofenamate label, drug interactionsWarfarin The effects of warfarin and NSAIDs on GI bleeding are synergistic, such that users of both drugs together have a risk of serious GI bleeding higher than users of either drug alone.
Source: FDA drug label (Meclofenamate Sodium), Mylan Pharmaceuticals Inc., effective April 15, 2026 (SPL set 96f19af4-de8f-4fd7-90d8-55fe6ebdd81d), via openFDA; the full label on DailyMed
What does the warfarin label say about meclofenamate?
Warfarin's label (effective May 29, 2026) does not name meclofenamate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Meclofenamate | Warfarin | |
|---|---|---|
| Labeled for | Fever, Pain, Rheumatoid arthritis, Osteoarthritis | Blood clots (DVT and PE), Atrial fibrillation |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $0.093 per tablet 2 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once