What the FDA labels say about taking them together
Mavacamten and voriconazole
Voriconazole's FDA label of February 26, 2026 names mavacamten in its drug interactions section; the mavacamten label PlainMeds reads does not name voriconazole.
Check it at the source: the mavacamten FDA label on DailyMed (effective April 17, 2025, Myokardia, Inc.); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).
What does the mavacamten label say about voriconazole?
Mavacamten's label (effective April 17, 2025) does not name voriconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (CAMZYOS), NDA214998 (Bristol), as published by Myokardia, Inc., effective April 17, 2025 (SPL set 669c936b-3ee6-4e36-8a22-79dd11b1255b), via openFDA; the full label on DailyMed
What does the voriconazole label say about mavacamten?
Voriconazole label, drug interactionsDrug/Drug Class (Mechanism of Interaction by Voriconazole): Mavacamten (CYP2C19/3A4/2C9 Inhibition); Drug Plasma Exposure (C max and AUC τ): Not Studied In Vivo or In Vitro, but Mavacamten Drug Plasma Exposure Likely to be Increased which may Increase the Risk of Heart Failure; Prevention or Management Recommendations: Refer to the prescribing information for mavacamten.
Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Mavacamten | Voriconazole | |
|---|---|---|
| Labeled for | n/a | Fungal infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $1.88 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once