What the FDA labels say about taking them together
Macimorelin and ziprasidone
Macimorelin's FDA label of February 18, 2026 names ziprasidone in its drug interactions section; the ziprasidone labels PlainMeds reads (2) do not name macimorelin. The macimorelin label: “DRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval may lead to development of torsade de pointes-type ventricular tachycardia.”
Check it at the source: the macimorelin FDA label on DailyMed (effective February 18, 2026, Aeterna Zentaris GmbH); the ziprasidone FDA label on DailyMed (effective July 20, 2026, Apotex Corp.).
What does the macimorelin label say about ziprasidone?
Macimorelin label, drug interactionsDRUG INTERACTIONS 7.1 Drugs that Prolong QT Interval Co-administration of MACRILEN with drugs that prolong the QT interval (such as antipsychotic medications (e.g., chlorpromazine, haloperidol, thioridazine, ziprasidone), antibiotics (e.g., moxifloxacin), Class 1A (e.g., quinidine, procainamide) and Class III (e.g., amiodarone, sotalol) antiarrhythmic medications or any other medications known to prolong the QT interval) may lead to development of torsade de pointes-type ventricular tachycardia.
Source: FDA drug label (Macrilen), Aeterna Zentaris GmbH, effective February 18, 2026 (SPL set aeb30f1a-4815-47ae-a2cb-b6b4e26372e1), via openFDA; the full label on DailyMed
What does the ziprasidone label say about macimorelin?
Ziprasidone's label (effective July 20, 2026) and its 1 other brand-application label do not name macimorelin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ziprasidone hydrochloride), Apotex Corp., effective July 20, 2026 (SPL set ccfd5ba2-7271-f3dd-4c98-7418c1a4b54a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Macimorelin | Ziprasidone | |
|---|---|---|
| Labeled for | n/a | Bipolar disorder, Schizophrenia |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.269 per capsule 20 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once