What the FDA labels say about taking them together
Loperamide and miglustat
Miglustat's FDA label of April 20, 2023 names loperamide in its warnings and precautions section; the loperamide label PlainMeds reads does not name miglustat. The miglustat label: “Diarrhea decreased over time with continued ZAVESCA treatment, and may respond to individualized diet modification, to taking ZAVESCA between meals, and/or to anti-diarrheal medications, most commonly loperamide.”
Check it at the source: the loperamide FDA label on DailyMed (effective June 3, 2026, Aurobindo Pharma Limited); the miglustat FDA label on DailyMed (effective April 20, 2023, Actelion Pharmaceuticals US, Inc.).
What does the loperamide label say about miglustat?
Loperamide's label (effective June 3, 2026) does not name miglustat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Loperamide Hydrochloride), Aurobindo Pharma Limited, effective June 3, 2026 (SPL set 8e4004be-bf79-4631-9e38-c4e7b6726313), via openFDA; the full label on DailyMed
What does the miglustat label say about loperamide?
Miglustat label, warnings and precautionsDiarrhea decreased over time with continued ZAVESCA treatment, and may respond to individualized diet modification (e.g., reduction of sucrose, lactose and other carbohydrate intake), to taking ZAVESCA between meals, and/or to anti-diarrheal medications, most commonly loperamide.
Source: FDA drug label (Zavesca), Actelion Pharmaceuticals US, Inc., effective April 20, 2023 (SPL set 817892d1-ee12-4632-85fc-57ccdf16d7b8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Loperamide | Miglustat | |
|---|---|---|
| Labeled for | Diarrhea | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0549 per capsule 2 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once