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What the FDA labels say about taking them together

Lomitapide and warfarin

Lomitapide's FDA label of March 30, 2026 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name lomitapide. The lomitapide label: “Lomitapide increases plasma concentrations of warfarin.”

Check it at the source: the lomitapide FDA label on DailyMed (effective March 30, 2026, Chiesi USA, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the lomitapide label say about warfarin?

Lomitapide label, drug interactions

Lomitapide increases plasma concentrations of warfarin.

Lomitapide label, warnings and precautions

Supratherapeutic or Subtherapeutic Anticoagulation with Warfarin JUXTAPID increases the plasma concentrations of warfarin.

Source: FDA drug label (Juxtapid), Chiesi USA, Inc., effective March 30, 2026 (SPL set 61a0be9d-ee58-43e0-b5cb-141011835081), via openFDA; the full label on DailyMed

What does the warfarin label say about lomitapide?

Warfarin's label (effective May 29, 2026) does not name lomitapide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Lomitapide generic labelers
19Warfarin generic labelers
LomitapideWarfarin
Labeled forHigh cholesterolBlood clots (DVT and PE), Atrial fibrillation
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?