What the FDA labels say about taking them together
Lithium and prochlorperazine
Prochlorperazine's FDA label of January 27, 2026 names lithium in its warnings section; the lithium labels PlainMeds reads (4) do not name prochlorperazine.
Check it at the source: the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA); the prochlorperazine FDA label on DailyMed (effective January 27, 2026, GLENMARK PHARMACEUTICALS INC., USA).
What does the lithium label say about prochlorperazine?
Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name prochlorperazine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed
What does the prochlorperazine label say about lithium?
Prochlorperazine label, warningsAn encephalopathic syndrome (characterized by weakness, lethargy, fever, tremulousness and confusion, extrapyramidal symptoms, leukocytosis, elevated serum enzymes, BUN and FBS) has occurred in a few patients treated with lithium plus an antipsychotic.
Source: FDA drug label (PROCHLORPERAZINE MALEATE), GLENMARK PHARMACEUTICALS INC., USA, effective January 27, 2026 (SPL set 9c806152-70d0-43eb-b183-b51b12b82b31), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lithium | Prochlorperazine | |
|---|---|---|
| Labeled for | Bipolar disorder | Nausea and vomiting, Schizophrenia, Anxiety |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.104 per capsule 300 mg capsule | $0.162 per tablet 10 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once