What the FDA labels say about taking them together
Linezolid and pseudoephedrine
Linezolid's FDA label of June 19, 2026 names pseudoephedrine in its warnings and precautions section; the pseudoephedrine label PlainMeds reads does not name linezolid. The linezolid label: “… medications: directly and indirectly acting sympathomimetic agents (e.g., pseudoephedrine), vasopressive agents, dopaminergic agents [ see Drug Interactions and Clinical Pharmacology ].”
Check it at the source: the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.); the pseudoephedrine FDA label on DailyMed (effective October 30, 2025, L. Perrigo Company).
What does the linezolid label say about pseudoephedrine?
Linezolid label, warnings and precautionsElevation of Blood Pressure Unless patients are monitored for potential increases in blood pressure, linezolid should not be administered to patients with uncontrolled hypertension, pheochromocytoma, thyrotoxicosis and/or patients taking any of the following types of medications: directly and indirectly acting sympathomimetic agents (e.g., pseudoephedrine), vasopressive agents (e.g., epinephrine, norepinephrine), dopaminergic agents (e.g., dopamine, dobutamine) [ see Drug Interactions (7) and Clinical Pharmacology (12.3) ].
Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed
What does the pseudoephedrine label say about linezolid?
Pseudoephedrine's label (effective October 30, 2025) does not name linezolid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Good Sense Suphedrine 12 Hour), L. Perrigo Company, effective October 30, 2025 (SPL set 1de8a7f6-e7bb-437d-8794-c4b9f43b89c9), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Linezolid | Pseudoephedrine | |
|---|---|---|
| Labeled for | Bacterial infections | Cough and cold |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.44 per tablet 600 mg tablet | $0.281 per tablet 120 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once