What the FDA labels say about taking them together
Linezolid and pretomanid
Pretomanid's FDA label of November 15, 2024 names linezolid in its contraindications section; the linezolid labels PlainMeds reads (3) do not name pretomanid. The pretomanid label: “Myelosuppression was reported with the use of the combination regimen of Pretomanid Tablets, bedaquiline, and linezolid. Monitor complete blood counts.”
Check it at the source: the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.); the pretomanid FDA label on DailyMed (effective November 15, 2024, Viatris Specialty LLC).
What does the linezolid label say about pretomanid?
Linezolid's label (effective June 19, 2026) and its 2 other brand-application labels do not name pretomanid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed
What does the pretomanid label say about linezolid?
Pretomanid label, contraindicationsCONTRAINDICATIONS Pretomanid Tablets used in the combination regimen with bedaquiline and linezolid are contraindicated in patients for whom bedaquiline and/or linezolid are contraindicated. Refer to the bedaquiline and linezolid prescribing information.
Pretomanid label, drug interactionsAvoid co-administration of the combination regimen of Pretomanid Tablets, bedaquiline, and linezolid with rifampin, efavirenz, or other strong or moderate CYP3A4 inducers.
Pretomanid label, warnings and precautionsMyelosuppression was reported with the use of the combination regimen of Pretomanid Tablets, bedaquiline, and linezolid. Monitor complete blood counts.
Source: FDA drug label (Pretomanid), NDA212862 (Mylan Ireland Ltd), as published by Viatris Specialty LLC, effective November 15, 2024 (SPL set f1906fc9-cb3c-4e13-8a4a-da76100c1bf3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Linezolid | Pretomanid | |
|---|---|---|
| Labeled for | Bacterial infections | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.44 per tablet 600 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once