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What the FDA labels say about taking them together

Linezolid and ozanimod

Ozanimod's FDA label of April 16, 2026 names linezolid in its drug interactions section; the linezolid labels PlainMeds reads (3) do not name ozanimod.

Check it at the source: the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.); the ozanimod FDA label on DailyMed (effective April 16, 2026, Celgene Corporation).

What does the linezolid label say about ozanimod?

Linezolid's label (effective June 19, 2026) and its 2 other brand-application labels do not name ozanimod in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed

What does the ozanimod label say about linezolid?

Ozanimod label, drug interactions

Clinical Impact: The effect of MAO inhibition on ozanimod and/or its metabolites has not been studied clinically. Potential effects on efficacy or safety with co-administration of MAO inhibitors because of altered exposures of ozanimod and/or its metabolites cannot be ruled out. Prevention or Management: Co-administration of ZEPOSIA with MAO inhibitors (e.g., selegiline, phenelzine, linezolid) is contraindicated. At least 14 days should elapse between discontinuation of ZEPOSIA and initiation of treatment with MAO inhibitors.

Source: FDA drug label (ZEPOSIA 7-Day Starter Pack), NDA209899 (Bristol), as published by Celgene Corporation, effective April 16, 2026 (SPL set 93ce2fab-edfb-4804-8074-963071de51e4), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

24Linezolid generic labelers
0Ozanimod generic labelers
LinezolidOzanimod
Labeled forBacterial infectionsn/a
Boxed warningNoNo
Pharmacy cost (NADAC)$1.44 per tablet 600 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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