What the FDA labels say about taking them together
Linezolid and lisdexamfetamine
Lisdexamfetamine's FDA label of April 30, 2026 names linezolid in its contraindications section; the linezolid labels PlainMeds reads (3) do not name lisdexamfetamine. The lisdexamfetamine label: “Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs, because of an increased risk of hypertensive crisis.”
Check it at the source: the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.); the lisdexamfetamine FDA label on DailyMed (effective April 30, 2026, Takeda Pharmaceuticals America, Inc.).
What does the linezolid label say about lisdexamfetamine?
Linezolid's label (effective June 19, 2026) and its 2 other brand-application labels do not name lisdexamfetamine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed
What does the lisdexamfetamine label say about linezolid?
Lisdexamfetamine label, contraindicationsPatients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping MAOIs (including MAOIs such as linezolid or intravenous methylene blue), because of an increased risk of hypertensive crisis [see Warnings and Precautions (5.7) and Drug Interactions (7.1) ].
Source: FDA drug label (Vyvanse), Takeda Pharmaceuticals America, Inc., effective April 30, 2026 (SPL set 704e4378-ca83-445c-8b45-3cfa51c1ecad), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Linezolid | Lisdexamfetamine | |
|---|---|---|
| Labeled for | Bacterial infections | ADHD, Binge eating disorder |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.44 per tablet 600 mg tablet | $2.44 per capsule 20 mg capsule |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once