What the FDA labels say about taking them together
Levothyroxine and vamorolone
Vamorolone's FDA label of January 22, 2026 names levothyroxine in its warnings and precautions section; the levothyroxine labels PlainMeds reads (4) do not name vamorolone. The vamorolone label: “When concomitant administration of AGAMREE and levothyroxine is required, administration of AGAMREE should precede the initiation of levothyroxine therapy to reduce the risk of adrenal crisis.”
Check it at the source: the levothyroxine FDA label on DailyMed (effective February 20, 2024, AbbVie Inc.); the vamorolone FDA label on DailyMed (effective January 22, 2026, Catalyst Pharmaceuticals, Inc.).
What does the levothyroxine label say about vamorolone?
Levothyroxine's label (effective February 20, 2024) and its 3 other brand-application labels do not name vamorolone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Synthroid), AbbVie Inc., effective February 20, 2024 (SPL set 1e11ad30-1041-4520-10b0-8f9d30d30fcc), via openFDA; the full label on DailyMed
What does the vamorolone label say about levothyroxine?
Vamorolone label, warnings and precautionsWhen concomitant administration of AGAMREE and levothyroxine is required, administration of AGAMREE should precede the initiation of levothyroxine therapy to reduce the risk of adrenal crisis.
Source: FDA drug label (AGAMREE), Catalyst Pharmaceuticals, Inc., effective January 22, 2026 (SPL set fb376f09-cf9c-42b5-b4dd-02d5bcd73211), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Levothyroxine | Vamorolone | |
|---|---|---|
| Labeled for | Hypothyroidism | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0588 per tablet 112 mcg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once