What the FDA labels say about taking them together
Levodopa and phenelzine
Levodopa's FDA label of July 20, 2026 names phenelzine in its contraindications section; the phenelzine label PlainMeds reads does not name levodopa. The levodopa label: “CONTRAINDICATIONS INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor or who have recently (within 2 weeks) taken a nonselective MAO inhibitor.”
Check it at the source: the levodopa FDA label on DailyMed (effective July 20, 2026, Merz Pharmaceuticals, LLC); the phenelzine FDA label on DailyMed (effective June 6, 2025, Parke-Davis Div of Pfizer Inc).
What does the levodopa label say about phenelzine?
Levodopa label, contraindicationsCONTRAINDICATIONS INBRIJA is contraindicated in patients currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g., phenelzine and tranylcypromine) or who have recently (within 2 weeks) taken a nonselective MAO inhibitor.
Source: FDA drug label (Inbrija), Merz Pharmaceuticals, LLC, effective July 20, 2026 (SPL set 077c0f39-a3a2-4b2b-a184-09131889dcfb), via openFDA; the full label on DailyMed
What does the phenelzine label say about levodopa?
Phenelzine's label (effective June 6, 2025) does not name levodopa in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Nardil), Parke-Davis Div of Pfizer Inc, effective June 6, 2025 (SPL set 513a41d0-37d4-4355-8a6d-a2c643bce6fa), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Levodopa | Phenelzine | |
|---|---|---|
| Labeled for | Parkinson's disease | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | n/a | $0.586 per tablet 15 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once