Lemborexant · larger labeled portfolio than Chlorzoxazone
SPL labels Lemborexant + Chlorzoxazone as minor; Lemborexant 9 / Chlorzoxazone 1 in that band.
Mechanism on file: Chlorzoxazone slows down the process your body uses to get rid of lemborexant. This may lead to higher levels of the sleep medicine in your blood.
FDA SPL severity: Minor
Lemborexant + Chlorzoxazone · SPL mechanism field
Chlorzoxazone slows down the process your body uses to get rid of lemborexant. This may lead to higher levels of the sleep medicine in your blood.
Minor band excerpt · Lemborexant with Chlorzoxazone
Examples: Strong CYP3A inhibitors: itraconazole, clarithromycin Moderate CYP3A inhibitors: fluconazole, verapamil Weak CYP3A inhibitors: chlorzoxazone, ranitidine Strong and Moderate CYP3A Inducers Clinical Impact: Concomitant use with a strong or moderate CYP3A inducer decreases lemborexant exposure, which may reduce DAYVIGO efficacy [see Clinical Pharmacology ( 12.3 )].
Lemborexant · 11 SPL pairs (broader portfolio than Chlorzoxazone)
- Bupropion minor
- Carbamazepine minor
- Clarithromycin minor
- Itraconazole minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.