Ciprofloxacin · more major-labeled pairs than Leflunomide
SPL labels Leflunomide + Ciprofloxacin as minor; Leflunomide 20 / Ciprofloxacin 13 in that band.
Mechanism on file: Leflunomide interferes with the proteins that help clear ciprofloxacin from your system. This can lead to higher levels of the antibiotic in your body.
FDA SPL severity: Minor
Leflunomide + Ciprofloxacin · SPL mechanism field
Leflunomide interferes with the proteins that help clear ciprofloxacin from your system. This can lead to higher levels of the antibiotic in your body.
Minor band excerpt · Leflunomide with Ciprofloxacin
In patients taking leflunomide, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased.
Leflunomide · 20 SPL pairs (broader portfolio than Ciprofloxacin)
- Alosetron minor
- Atorvastatin minor
- Cimetidine minor
- Duloxetine minor
Ciprofloxacin · 1 major-labeled pairs (vs Leflunomide's 0)
- Carbamazepine minor
- Clozapine minor
- Cyclosporine minor
- Duloxetine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.