What the FDA labels say about taking them together
Diltiazem and itraconazole
Itraconazole's FDA label of July 13, 2026 names diltiazem in its drug interactions section; the diltiazem labels PlainMeds reads (4) do not name itraconazole. The itraconazole label: “Diltiazem Other dihydropyridines Verapamil Monitor for adverse reactions.”
Check it at the source: the diltiazem FDA label on DailyMed (effective August 7, 2026, Bausch Health US, LLC); the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.).
What does the diltiazem label say about itraconazole?
Diltiazem's label (effective August 7, 2026) and its 3 other brand-application labels do not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (TIAZAC EXTENDED RELEASE), Bausch Health US, LLC, effective August 7, 2026 (SPL set c567fe7e-887e-4291-a0d1-2dd3f25cbf25), via openFDA; the full label on DailyMed
What does the itraconazole label say about diltiazem?
Itraconazole label, drug interactionsDiltiazem Other dihydropyridines Verapamil Monitor for adverse reactions.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Diltiazem | Itraconazole | |
|---|---|---|
| Labeled for | High blood pressure, Angina, Atrial fibrillation | Fungal infections |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.144 per capsule 24h ER(cd) 120 mg capsule | $0.910 per capsule 100 mg capsule |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once