What the FDA labels say about taking them together

Isoflurane and vecuronium

Isoflurane's FDA label of January 5, 2026 names vecuronium in its drug interactions section, and vecuronium's label names isoflurane too. The isoflurane label: “In general, anesthetic concentrations of FORANE at equilibrium reduce the ED 95 of succinylcholine, atracurium, pancuronium, rocuronium and vecuronium by approximately 25 to 40% or more compared to N 2 O/opioid …”

Check it at the source: the isoflurane FDA label on DailyMed (effective January 5, 2026, Shandong New Time Pharmaceutical Co., Ltd.); the vecuronium FDA label on DailyMed (effective June 18, 2025, Meitheal Pharmaceuticals Inc.).

What does the isoflurane label say about vecuronium?

Isoflurane label, drug interactions
In general, anesthetic concentrations of isoflurane at equilibrium reduce the ED 95 of succinylcholine, atracurium, pancuronium, rocuronium and vecuronium by approximately 25 to 40% or more compared to N 2 O/opioid anesthesia.

Source: FDA drug label (Forane, NDA017624), Baxter Healthcare Corporation, effective December 9, 2024 (SPL set 3d30eb8d-a62e-475f-926b-78ba63bee9c8), via openFDA

Source: FDA drug label (Isoflurane), Shandong New Time Pharmaceutical Co., Ltd., effective January 5, 2026 (SPL set 662ceaf6-650b-4dea-bbee-652f46426024), via openFDA; the full label on DailyMed

What does the vecuronium label say about isoflurane?

Vecuronium label, drug interactions
Inhalational Anesthetics Use of volatile inhalational anesthetics such as enflurane, isoflurane, and halothane with vecuronium will enhance neuromuscular blockade.

Source: FDA drug label (Vecuronium Bromide), Meitheal Pharmaceuticals Inc., effective June 18, 2025 (SPL set 53653418-0464-4cd2-a987-3d31be36098f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Isoflurane generic labelers

10Vecuronium generic labelers

	Isoflurane	Vecuronium
Labeled for	n/a	n/a
Boxed warning	No	Yes
Pharmacy cost (NADAC)	n/a	n/a
Shortage now	No current entry	No current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?

Isoflurane: the full record
Vecuronium: the full record
Check more medicines together: up to five at once