What the FDA labels say about taking them together
Isocarboxazid and linezolid
Linezolid's FDA label of June 19, 2026 names isocarboxazid in its contraindications section; the isocarboxazid label PlainMeds reads does not name linezolid.
Check it at the source: the isocarboxazid FDA label on DailyMed (effective April 21, 2026, Lifsa Drugs LLC); the linezolid FDA label on DailyMed (effective June 19, 2026, Hospira, Inc.).
What does the isocarboxazid label say about linezolid?
Isocarboxazid's label (effective April 21, 2026) does not name linezolid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (MARPLAN), Lifsa Drugs LLC, effective April 21, 2026 (SPL set 95fde749-44ad-4668-86c4-0ff17bca0074), via openFDA; the full label on DailyMed
What does the linezolid label say about isocarboxazid?
Linezolid label, contraindicationsLinezolid should not be used in patients taking any medicinal product which inhibits monoamine oxidases A or B (e.g., phenelzine, isocarboxazid) or within two weeks of taking any such medicinal product.
Source: FDA drug label (Linezolid), Hospira, Inc., effective June 19, 2026 (SPL set c401f1a8-cc37-461b-bfef-f2e156629bf8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Isocarboxazid | Linezolid | |
|---|---|---|
| Labeled for | Depression | Bacterial infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $1.44 per tablet 600 mg tablet |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once