What the FDA labels say about taking them together
Imiglucerase and miglustat
Miglustat's FDA label of April 20, 2023 names imiglucerase in its drug interactions section; the imiglucerase label PlainMeds reads does not name miglustat. The miglustat label: “DRUG INTERACTIONS While co-administration of ZAVESCA appeared to increase the clearance of imiglucerase by 70%, these results are not conclusive because of the small number of patients studied and because patients took …”
Check it at the source: the imiglucerase FDA label on DailyMed (effective August 27, 2026, Genzyme Corporation); the miglustat FDA label on DailyMed (effective April 20, 2023, Actelion Pharmaceuticals US, Inc.).
What does the imiglucerase label say about miglustat?
Imiglucerase's label (effective August 27, 2026) does not name miglustat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cerezyme), Genzyme Corporation, effective August 27, 2026 (SPL set df60f030-866b-4374-a31f-8ae3f6b45c38), via openFDA; the full label on DailyMed
What does the miglustat label say about imiglucerase?
Miglustat label, drug interactionsDRUG INTERACTIONS While co-administration of ZAVESCA appeared to increase the clearance of imiglucerase by 70%, these results are not conclusive because of the small number of patients studied and because patients took variable doses of imiglucerase [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Zavesca), Actelion Pharmaceuticals US, Inc., effective April 20, 2023 (SPL set 817892d1-ee12-4632-85fc-57ccdf16d7b8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Imiglucerase | Miglustat | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once