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What the FDA labels say about taking them together

Granisetron and quizartinib

Quizartinib's FDA label of April 16, 2026 names granisetron in its drug interactions section; the granisetron labels PlainMeds reads (3) do not name quizartinib. The quizartinib label: “… prolonging drugs include but are not limited to antifungal azoles, ondansetron, granisetron, azithromycin, pentamidine, doxycycline, moxifloxacin, atovaquone, prochlorperazine, and tacrolimus.”

Check it at the source: the granisetron FDA label on DailyMed (effective August 31, 2017, Mylan Institutional LLC); the quizartinib FDA label on DailyMed (effective April 16, 2026, Daiichi Sankyo Inc.).

What does the granisetron label say about quizartinib?

Granisetron's label (effective August 31, 2017) and its 2 other brand-application labels do not name quizartinib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Granisetron Hydrochloride), Mylan Institutional LLC, effective August 31, 2017 (SPL set 8d88adba-7f5e-4e97-84b3-6ca8ec98c023), via openFDA; the full label on DailyMed

What does the quizartinib label say about granisetron?

Quizartinib label, drug interactions

QT Interval Prolonging Drugs Clinical Impact VANFLYTA prolongs the QT/QTc interval. Coadministration of VANFLYTA with other drugs that prolong the QT interval may further increase the incidence of QT prolongation [see Warnings and Precautions (5.1) and Clinical Pharmacology (12.2) ]. Prevention or Management Monitor patients more frequently with ECG if co-administration of VANFLYTA with drugs known to prolong the QT interval is required. Examples of QT prolonging drugs include but are not limited to antifungal azoles, ondansetron, granisetron, azithromycin, pentamidine, doxycycline, moxifloxacin, atovaquone, prochlorperazine, and tacrolimus.

Source: FDA drug label (VANFLYTA), Daiichi Sankyo Inc., effective April 16, 2026 (SPL set 29cdbcfe-497d-4e78-bb7b-2d4acafe8e86), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Granisetron generic labelers
0Quizartinib generic labelers
GranisetronQuizartinib
Labeled forNausea and vomitingLeukemia, lymphoma and myeloma
Boxed warningNoYes
Pharmacy cost (NADAC)$1.31 per tablet 1 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?