What the FDA labels say about taking them together
Glycopyrrolate and levodopa
Glycopyrrolate's FDA label (Cuvposa) of December 19, 2024 names levodopa in its drug interactions section; the levodopa label PlainMeds reads does not name glycopyrrolate. The glycopyrrolate label: “Consider dose reduction when used with glycopyrrolate. Haloperidol or levodopa: Glycopyrrolate may decrease serum levels of haloperidol or levodopa.”
Check it at the source: the glycopyrrolate FDA label on DailyMed (effective October 9, 2025, Hikma Pharmaceuticals USA Inc.); the levodopa FDA label on DailyMed (effective July 20, 2026, Merz Pharmaceuticals, LLC).
What does the glycopyrrolate label say about levodopa?
Cuvposa label (Merz Pharmaceuticals, LLC, December 19, 2024), drug interactionsConsider dose reduction when used with glycopyrrolate. ( 7 ) Haloperidol or levodopa: Glycopyrrolate may decrease serum levels of haloperidol or levodopa.
Source: FDA drug label (Cuvposa, NDA022571), Merz Pharmaceuticals, LLC, effective December 19, 2024 (SPL set d200bd44-9856-4104-a29e-a4cca3db6737), via openFDA
Source: FDA drug label (Glycopyrrolate), Hikma Pharmaceuticals USA Inc., effective October 9, 2025 (SPL set 960d2dd0-008d-4ec1-ba2e-9388b28b23e2), via openFDA; the full label on DailyMed
What does the levodopa label say about glycopyrrolate?
Levodopa's label (effective July 20, 2026) does not name glycopyrrolate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Inbrija), Merz Pharmaceuticals, LLC, effective July 20, 2026 (SPL set 077c0f39-a3a2-4b2b-a184-09131889dcfb), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Glycopyrrolate | Levodopa | |
|---|---|---|
| Labeled for | n/a | Parkinson's disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.51 per mL 0.2 mg/mL vial | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once