What the FDA labels say about taking them together
Glycopyrrolate and haloperidol
Glycopyrrolate's FDA label (Cuvposa) of December 19, 2024 names haloperidol in its drug interactions section; the haloperidol labels PlainMeds reads (2) do not name glycopyrrolate. The glycopyrrolate label: “Consider dose reduction when used with glycopyrrolate. Haloperidol or levodopa: Glycopyrrolate may decrease serum levels of haloperidol or levodopa.”
Check it at the source: the glycopyrrolate FDA label on DailyMed (effective October 9, 2025, Hikma Pharmaceuticals USA Inc.); the haloperidol FDA label on DailyMed (effective April 23, 2026, PD-Rx Pharmaceuticals, Inc.).
What does the glycopyrrolate label say about haloperidol?
Cuvposa label (Merz Pharmaceuticals, LLC, December 19, 2024), drug interactionsConsider dose reduction when used with glycopyrrolate. ( 7 ) Haloperidol or levodopa: Glycopyrrolate may decrease serum levels of haloperidol or levodopa.
Source: FDA drug label (Cuvposa, NDA022571), Merz Pharmaceuticals, LLC, effective December 19, 2024 (SPL set d200bd44-9856-4104-a29e-a4cca3db6737), via openFDA
Source: FDA drug label (Glycopyrrolate), Hikma Pharmaceuticals USA Inc., effective October 9, 2025 (SPL set 960d2dd0-008d-4ec1-ba2e-9388b28b23e2), via openFDA; the full label on DailyMed
What does the haloperidol label say about glycopyrrolate?
Haloperidol's label (effective April 23, 2026) and its 1 other brand-application label do not name glycopyrrolate in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Haloperidol), PD-Rx Pharmaceuticals, Inc., effective April 23, 2026 (SPL set 533b0b4c-cbd6-4ec0-a333-8b04b5b43a1d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Glycopyrrolate | Haloperidol | |
|---|---|---|
| Labeled for | n/a | Schizophrenia |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.51 per mL 0.2 mg/mL vial | $15.60 per mL 100 mg/mL vial |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once