Glucagon and Warfarin Interaction
Drug interaction information between Glucagon and Warfarin.
Glucagon and Warfarin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Glucagon and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Glucagon can make warfarin more powerful, which increases the risk of bleeding.
FDA Label Information
Warfarin Clinical Impact: Glucagon for Injection may increase the anticoagulant effect of warfarin. Intervention: Monitor patients for unusual bruising or bleeding, as adjustments in warfarin dosage may be required. ( 7 ) • Warfarin : Glucagon for Injection may increase the anticoagulant effect of warfarin.
Glucagon Also Interacts With
- Indomethacin minor
- Glimepiride minor
- Insulin Aspart minor
- Insulin Degludec minor
- Insulin Detemir minor
Warfarin Also Interacts With
- Fluoxetine major
- Tamoxifen major
- Ibuprofen moderate
- Aspirin moderate
- Diclofenac moderate
Frequently Asked Questions
What SPL severity band is on file for Glucagon + Warfarin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Warfarin has 163 labeled pairs on file vs Glucagon's 14. In the minor band specifically: Glucagon has 14 (also Indomethacin, Glimepiride, Insulin Aspart, Insulin Degludec); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).
What mechanism field is on file for Glucagon and Warfarin?
Glucagon can make warfarin more powerful, which increases the risk of bleeding.
Warfarin carries more major-labeled pairs than Glucagon
SPL source-record counts only. This page's band is minor · classes on file: Glucagon (Glucagon (Hypoglycemia Rescue)); Warfarin (Vitamin K Antagonist (Anticoagulant)).
Warfarin has 2 major-labeled pairs vs Glucagon's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 14 minor · 14 total
- Other minor peers for Glucagon
- Indomethacin
- Glimepiride
- Insulin Aspart
- Insulin Degludec
2 major · 28 moderate · 133 minor · 163 total
- Other minor peers for Warfarin
- Atorvastatin
- Amlodipine
- Omeprazole
- Famotidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.