What the FDA labels say about taking them together
Glimepiride and miconazole
Glimepiride's FDA label of May 12, 2025 names miconazole in its drug interactions section; the miconazole labels PlainMeds reads (2) do not name glimepiride. The glimepiride label: “Severe hypoglycemia can occur when glimepiride and oral miconazole are used concomitantly. Cytochrome P450 2C9 interactions:”
Check it at the source: the glimepiride FDA label on DailyMed (effective May 12, 2025, Micro Labs Limited); the miconazole FDA label on DailyMed (effective July 21, 2026, WALGREEN COMPANY).
What does the glimepiride label say about miconazole?
Glimepiride label, drug interactionsSevere hypoglycemia can occur when glimepiride and oral miconazole are used concomitantly. ( 7.2 ) Cytochrome P450 2C9 interactions:
Source: FDA drug label (Glimepiride), Micro Labs Limited, effective May 12, 2025 (SPL set 60e9397e-83b9-489e-9683-6f87e458bbaa), via openFDA; the full label on DailyMed
What does the miconazole label say about glimepiride?
Miconazole's label (effective July 21, 2026) and its 1 other brand-application label do not name glimepiride in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Miconazole 3 Walgreen Company), NDA020670 (Medtech Products), as published by WALGREEN COMPANY, effective July 21, 2026 (SPL set 32b373be-9c8e-49b0-a796-8d87f6a20cef), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Glimepiride | Miconazole | |
|---|---|---|
| Labeled for | Type 2 diabetes | Fungal infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.0507 per tablet 4 mg tablet | $0.120 per gram 2% topical cream |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once