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What the FDA labels say about taking them together

Gentamicin and streptomycin

Streptomycin's FDA label of January 21, 2026 names gentamicin in its boxed warning section; the gentamicin label PlainMeds reads does not name streptomycin.

Check it at the source: the gentamicin FDA label on DailyMed (effective July 22, 2024, Bausch & Lomb Incorporated); the streptomycin FDA label on DailyMed (effective January 21, 2026, XGen Pharmaceuticals DJB, Inc.).

What does the gentamicin label say about streptomycin?

Gentamicin's label (effective July 22, 2024) does not name streptomycin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Gentamicin Sulfate), Bausch & Lomb Incorporated, effective July 22, 2024 (SPL set 41d01350-5c4b-42fc-be5f-986ceec02bd3), via openFDA; the full label on DailyMed

What does the streptomycin label say about gentamicin?

Streptomycin label, boxed warning

THE CONCURRENT OR SEQUENTIAL USE OF OTHER NEUROTOXIC AND/OR NEPHROTOXIC DRUGS WITH STREPTOMYCIN SULFATE, INCLUDING NEOMYCIN, KANAMYCIN, GENTAMICIN, CEPHALORIDINE, PAROMOMYCIN, VIOMYCIN, POLYMYXIN B, COLISTIN, TOBRAMYCIN AND CYCLOSPORINE SHOULD BE AVOIDED.

Source: FDA drug label (Streptomycin), XGen Pharmaceuticals DJB, Inc., effective January 21, 2026 (SPL set abd1f64e-4283-4370-aae8-3666316aa36e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

24Gentamicin generic labelers
1Streptomycin generic labelers
GentamicinStreptomycin
Labeled forBacterial infectionsn/a
Boxed warningNoYes
Pharmacy cost (NADAC)$1.30 per mL 80 mg/2 mL vialn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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