What the FDA labels say about taking them together
Gentamicin and indomethacin
Indomethacin's FDA label (Indomethacin) of January 19, 2026 names gentamicin in its drug interactions section; the gentamicin label PlainMeds reads does not name indomethacin. The indomethacin label: “In one study of premature infants treated with Indomethacin for Injection and also receiving either gentamicin or amikacin, both peak and trough levels of these aminoglycosides were significantly elevated.”
Check it at the source: the gentamicin FDA label on DailyMed (effective July 22, 2024, Bausch & Lomb Incorporated); the indomethacin FDA label on DailyMed (effective December 19, 2025, Glenmark Pharmaceuticals Inc., USA).
What does the gentamicin label say about indomethacin?
Gentamicin's label (effective July 22, 2024) does not name indomethacin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Gentamicin Sulfate), Bausch & Lomb Incorporated, effective July 22, 2024 (SPL set 41d01350-5c4b-42fc-be5f-986ceec02bd3), via openFDA; the full label on DailyMed
What does the indomethacin label say about gentamicin?
Indomethacin label (Fresenius Kabi USA, LLC, January 19, 2026), drug interactionsIn one study of premature infants treated with Indomethacin for Injection and also receiving either gentamicin or amikacin, both peak and trough levels of these aminoglycosides were significantly elevated.
Source: FDA drug label (Indomethacin, NDA022536), Fresenius Kabi USA, LLC, effective January 19, 2026 (SPL set ec482425-358c-4500-8f5d-79c1379c1fa8), via openFDA
Source: FDA drug label (Indomethacin), Glenmark Pharmaceuticals Inc., USA, effective December 19, 2025 (SPL set f7ed39e2-5431-4e47-935c-c7441d058f94), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Gentamicin | Indomethacin | |
|---|---|---|
| Labeled for | Bacterial infections | Rheumatoid arthritis, Osteoarthritis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.30 per mL 80 mg/2 mL vial | $0.210 per capsule 75 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once