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What the FDA labels say about taking them together

Gatifloxacin and iloperidone

Iloperidone's FDA label of May 6, 2026 names gatifloxacin in its warnings and precautions section; the gatifloxacin label PlainMeds reads does not name iloperidone.

Check it at the source: the gatifloxacin FDA label on DailyMed (effective September 8, 2016, Allergan, Inc.); the iloperidone FDA label on DailyMed (effective May 6, 2026, Vanda Pharmaceuticals Inc.).

What does the gatifloxacin label say about iloperidone?

Gatifloxacin's label (effective September 8, 2016) does not name iloperidone in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (ZYMAXID), NDA022548 (Abbvie), as published by Allergan, Inc., effective September 8, 2016 (SPL set 1160b16c-929a-4e85-9c0b-1d8c96a7678b), via openFDA; the full label on DailyMed

What does the iloperidone label say about gatifloxacin?

Iloperidone label, warnings and precautions

The use of FANAPT should be avoided in combination with other drugs that are known to prolong QTc including Class 1A (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic medications, antipsychotic medications (e.g., chlorpromazine, thioridazine), antibiotics (e.g., gatifloxacin, moxifloxacin), or any other class of medications known to prolong the QTc interval (e.g., pentamidine, levomethadyl acetate, methadone).

Source: FDA drug label (FANAPT), Vanda Pharmaceuticals Inc., effective May 6, 2026 (SPL set 33f60b40-3fca-11de-8f56-0002a5d5c51b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

3Gatifloxacin generic labelers
1Iloperidone generic labelers
GatifloxacinIloperidone
Labeled forn/aSchizophrenia, Bipolar disorder
Boxed warningNoYes
Pharmacy cost (NADAC)$8.85 per mL 0.5% eye drops$60.01 per tablet 12 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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