What the FDA labels say about taking them together
Furosemide and teriflunomide
Teriflunomide's FDA label of February 20, 2026 names furosemide in its drug interactions section; the furosemide labels PlainMeds reads (4) do not name teriflunomide. The teriflunomide label: “In patients taking AUBAGIO, exposure of drugs which are OAT3 substrates may be increased.”
Check it at the source: the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC); the teriflunomide FDA label on DailyMed (effective February 20, 2026, Genzyme Corporation).
What does the furosemide label say about teriflunomide?
Furosemide's label (effective September 30, 2025) and its 3 other brand-application labels do not name teriflunomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
What does the teriflunomide label say about furosemide?
Teriflunomide label, drug interactionsIn patients taking AUBAGIO, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased.
Source: FDA drug label (Aubagio), NDA202992 (Sanofi Aventis Us), as published by Genzyme Corporation, effective February 20, 2026 (SPL set 4650d12c-b9c8-4525-b07f-a2d773eca155), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Furosemide | Teriflunomide | |
|---|---|---|
| Labeled for | Heart failure, High blood pressure, Edema (fluid retention) | Multiple sclerosis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.490 per mL 20 mg/2 mL vial | $0.233 per tablet 14 mg tablet |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once