What the FDA labels say about taking them together
Furosemide and sucralfate
Furosemide's FDA label of September 30, 2025 names sucralfate in its drug interactions section; the sucralfate labels PlainMeds reads (2) do not name furosemide. The furosemide label: “Simultaneous administration of sucralfate and LASIX tablets may reduce the natriuretic and antihypertensive effects of LASIX.”
Check it at the source: the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC); the sucralfate FDA label on DailyMed (effective September 2, 2026, Preferred Pharmaceuticals Inc.).
What does the furosemide label say about sucralfate?
Furosemide label, drug interactionsSimultaneous administration of sucralfate and LASIX tablets may reduce the natriuretic and antihypertensive effects of LASIX.
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
What does the sucralfate label say about furosemide?
Sucralfate's label (effective September 2, 2026) and its 1 other brand-application label do not name furosemide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Sucralfate), NDA018333 (Abbvie), as published by Preferred Pharmaceuticals Inc., effective September 2, 2026 (SPL set 536b8c00-13ab-4397-a754-63a1c92bf883), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Furosemide | Sucralfate | |
|---|---|---|
| Labeled for | Heart failure, High blood pressure, Edema (fluid retention) | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.490 per mL 20 mg/2 mL vial | $0.173 per tablet 1 g tablet |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once