What the FDA labels say about taking them together
Furosemide and succinylcholine
Furosemide's FDA label of September 30, 2025 names succinylcholine in its drug interactions section; the succinylcholine labels PlainMeds reads (2) do not name furosemide. The furosemide label: “Monitor for skeletal muscle effect.”
Check it at the source: the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC); the succinylcholine FDA label on DailyMed (effective August 18, 2026, Hospira, Inc.).
What does the furosemide label say about succinylcholine?
Furosemide label, drug interactionsLASIX has a tendency to antagonize the skeletal muscle-relaxing effect of tubocurarine and may potentiate the action of succinylcholine.
Furoscix label (scPharmaceuticals Inc., a wholly owned subsidiary of MannKind Corporation, July 31, 2026), drug interactionsDrug/Substance Class or Name: Paralytic agents; Drug Interaction Effect: Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine.; Recommendations: Monitor for skeletal muscle effect.
Source: FDA drug label (Furosemide, NDA018267), Hikma Pharmaceuticals USA Inc., effective March 10, 2025 (SPL set ddfc41a9-37d4-49c1-bbf3-969a98cd649c), via openFDA
Source: FDA drug label (Furoscix, NDA209988), scPharmaceuticals Inc., a wholly owned subsidiary of MannKind Corporation, effective July 31, 2026 (SPL set eac958dd-8d43-e44e-e053-2995a90a4d5e), via openFDA
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
What does the succinylcholine label say about furosemide?
Succinylcholine's label (effective August 18, 2026) and its 1 other brand-application label do not name furosemide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (QUELICIN), Hospira, Inc., effective August 18, 2026 (SPL set fb08161e-7711-406d-e7b3-ea4515c07983), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Furosemide | Succinylcholine | |
|---|---|---|
| Labeled for | Heart failure, High blood pressure, Edema (fluid retention) | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.490 per mL 20 mg/2 mL vial | n/a |
| Shortage now | In shortage | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once