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What the FDA labels say about taking them together

Furosemide and streptomycin

Streptomycin's FDA label of January 21, 2026 names furosemide in its drug interactions section; the furosemide labels PlainMeds reads (4) do not name streptomycin.

Check it at the source: the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC); the streptomycin FDA label on DailyMed (effective January 21, 2026, XGen Pharmaceuticals DJB, Inc.).

What does the furosemide label say about streptomycin?

Furosemide's label (effective September 30, 2025) and its 3 other brand-application labels do not name streptomycin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed

What does the streptomycin label say about furosemide?

Streptomycin label, drug interactions

Drug Interactions The ototoxic effects of the aminoglycosides, including streptomycin, are potentiated by the coadministration of ethacrynic acid, furosemide, mannitol and possibly other diuretics.

Source: FDA drug label (Streptomycin), XGen Pharmaceuticals DJB, Inc., effective January 21, 2026 (SPL set abd1f64e-4283-4370-aae8-3666316aa36e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

52Furosemide generic labelers
1Streptomycin generic labelers
FurosemideStreptomycin
Labeled forHeart failure, High blood pressure, Edema (fluid retention)n/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.490 per mL 20 mg/2 mL vialn/a
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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