Skip to main content

What the FDA labels say about taking them together

Foscarbidopa/foslevodopa and phenelzine

Foscarbidopa/foslevodopa's FDA label of March 19, 2026 names phenelzine in its drug interactions section; the phenelzine label PlainMeds reads does not name foscarbidopa/foslevodopa. The foscarbidopa/foslevodopa label: “Oxidase (MAO) Inhibitors Nonselective MAO Inhibitors The use of nonselective MAO inhibitors with VYALEV is contraindicated.”

Check it at the source: the foscarbidopa/foslevodopa FDA label on DailyMed (effective March 19, 2026, AbbVie Inc.); the phenelzine FDA label on DailyMed (effective June 6, 2025, Parke-Davis Div of Pfizer Inc).

What does the foscarbidopa/foslevodopa label say about phenelzine?

Foscarbidopa/foslevodopa label, drug interactions

Oxidase (MAO) Inhibitors Nonselective MAO Inhibitors The use of nonselective MAO inhibitors (e.g., phenelzine and tranylcypromine) with VYALEV is contraindicated [see Contraindications ( 4 ) ].

Source: FDA drug label (Vyalev), AbbVie Inc., effective March 19, 2026 (SPL set 28e806e4-951c-40a9-9f0c-d0929caf054c), via openFDA; the full label on DailyMed

What does the phenelzine label say about foscarbidopa/foslevodopa?

Phenelzine's label (effective June 6, 2025) does not name foscarbidopa/foslevodopa in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Nardil), Parke-Davis Div of Pfizer Inc, effective June 6, 2025 (SPL set 513a41d0-37d4-4355-8a6d-a2c643bce6fa), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Foscarbidopa/foslevodopa generic labelers
1Phenelzine generic labelers
Foscarbidopa/foslevodopaPhenelzine
Labeled forParkinson's diseasen/a
Boxed warningNoYes
Pharmacy cost (NADAC)n/a$0.586 per tablet 15 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?