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What the FDA labels say about taking them together

Fosamprenavir and verapamil

Fosamprenavir's FDA label of September 15, 2023 names verapamil in its drug interactions section; the verapamil labels PlainMeds reads (4) do not name fosamprenavir. The fosamprenavir label: “Use with caution. Clinical monitoring of patients is recommended.”

Check it at the source: the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.); the verapamil FDA label on DailyMed (effective April 6, 2026, Zydus Pharmaceuticals (USA) Inc.).

What does the fosamprenavir label say about verapamil?

Fosamprenavir label, drug interactions

Concomitant Drug Class/Drug Name: Calcium channel blockers: Diltiazem, felodipine, nifedipine, nicardipine, nimodipine, verapamil, amlodipine, nisoldipine, isradipine; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Calcium channel blockers; Clinical Comment: Use with caution. Clinical monitoring of patients is recommended.

Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed

What does the verapamil label say about fosamprenavir?

Verapamil's label (effective April 6, 2026) and its 3 other brand-application labels do not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Verapamil hydrochloride), Zydus Pharmaceuticals (USA) Inc., effective April 6, 2026 (SPL set e19ab8d8-dae5-489d-9805-7e7407bea06d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Fosamprenavir generic labelers
43Verapamil generic labelers
FosamprenavirVerapamil
Labeled forHIVHigh blood pressure, Atrial fibrillation, Angina
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.191 per tablet 180 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?