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What the FDA labels say about taking them together

Diltiazem and fluvoxamine

Fluvoxamine's FDA label of June 27, 2026 names diltiazem in its drug interactions section; the diltiazem labels PlainMeds reads (4) do not name fluvoxamine.

Check it at the source: the diltiazem FDA label on DailyMed (effective August 7, 2026, Bausch Health US, LLC); the fluvoxamine FDA label on DailyMed (effective June 27, 2026, Zydus Pharmaceuticals USA Inc.).

What does the diltiazem label say about fluvoxamine?

Diltiazem's label (effective August 7, 2026) and its 3 other brand-application labels do not name fluvoxamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (TIAZAC EXTENDED RELEASE), Bausch Health US, LLC, effective August 7, 2026 (SPL set c567fe7e-887e-4291-a0d1-2dd3f25cbf25), via openFDA; the full label on DailyMed

What does the fluvoxamine label say about diltiazem?

Fluvoxamine label, drug interactions

Bradycardia has been reported with the coadministration of immediate-release fluvoxamine maleate tablets and diltiazem.

Source: FDA drug label (Fluvoxamine Maleate, NDA021519), ANI Pharmaceuticals, Inc., effective August 4, 2025 (SPL set 7ecd83ec-88f5-4f85-9cc2-9068375d8820), via openFDA

Source: FDA drug label (Fluvoxamine maleate extended-release), Zydus Pharmaceuticals USA Inc., effective June 27, 2026 (SPL set 6c71d4f6-54b5-4d3a-8d2f-b7773c92c32e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

50Diltiazem generic labelers
16Fluvoxamine generic labelers
DiltiazemFluvoxamine
Labeled forHigh blood pressure, Angina, Atrial fibrillationn/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.144 per capsule 24h ER(cd) 120 mg capsule$4.08 per capsule 100 mg capsule
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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