Fluvoxamine · more major-labeled pairs than Alprazolam

SPL labels Fluvoxamine + Alprazolam as minor; Fluvoxamine 36 / Alprazolam 20 in that band.

Mechanism on file: Fluvoxamine blocks the process your body uses to clear alprazolam. This causes the drug to build up in your system, which can make you feel much more tired.

FDA SPL severity: Minor

Fluvoxamine

Full Fluvoxamine label record

Selective Serotonin Reuptake Inhibitor (SSRI)

Alprazolam

Full Alprazolam label record

Benzodiazepine

Fluvoxamine + Alprazolam · SPL mechanism field

Fluvoxamine blocks the process your body uses to clear alprazolam. This causes the drug to build up in your system, which can make you feel much more tired.

Minor band excerpt · Fluvoxamine with Alprazolam

Examples Nefazodone, fluvoxamine, cimetidine, erythromycin CYP3A Inducers Clinical implication Concomitant use of CYP3A inducers can increase alprazolam metabolism and therefore can decease plasma levels of alprazolam [see Clinical Pharmacology (12.3) ] .

Fluvoxamine · 1 major-labeled pairs (vs Alprazolam's 0)

View all Fluvoxamine interactions →

Alprazolam · 20 minor + 27 total pairs

View all Alprazolam interactions →

FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.