Fluvoxamine · larger labeled portfolio than Amitriptyline

SPL labels Fluvoxamine + Amitriptyline as minor; Fluvoxamine 36 / Amitriptyline 20 in that band.

Mechanism on file: Fluvoxamine prevents your body from breaking down amitriptyline properly. This leads to a significant increase in the amount of amitriptyline in your bloodstream.

FDA SPL severity: Minor

Fluvoxamine

Full Fluvoxamine label record

Selective Serotonin Reuptake Inhibitor (SSRI)

Amitriptyline

Full Amitriptyline label record

Tricyclic Antidepressant (TCA)

Fluvoxamine + Amitriptyline · SPL mechanism field

Fluvoxamine prevents your body from breaking down amitriptyline properly. This leads to a significant increase in the amount of amitriptyline in your bloodstream.

Minor band excerpt · Fluvoxamine with Amitriptyline

Tricyclic Antidepressants (TCAs): Significantly increased plasma TCA levels have been reported with the coadministration of immediate-release fluvoxamine maleate tablets and amitriptyline, clomipramine or imipramine.

Fluvoxamine · 40 SPL pairs (broader portfolio than Amitriptyline)

View all Fluvoxamine interactions →

Amitriptyline · 20 minor + 21 total pairs

View all Amitriptyline interactions →

FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.