Colchicine · more major-labeled pairs than Fluvastatin
SPL labels Fluvastatin + Colchicine as minor; Fluvastatin 5 / Colchicine 15 in that band.
Mechanism on file: Combining these medications can cause muscle damage or weakness because both drugs can affect muscle health.
FDA SPL severity: Minor
Fluvastatin + Colchicine · SPL mechanism field
Combining these medications can cause muscle damage or weakness because both drugs can affect muscle health.
Minor band excerpt · Fluvastatin with Colchicine
Other Potentially Significant Drug Interactions Concomitant Drug Class or Food Noted or Anticipated Outcome Clinical Comment HMG-CoA Reductase Inhibitors: atorvastatin, fluvastatin, lovastatin, pravastatin, simvastatin Pharmacokinetic and/or pharmacodynamic interaction: the addition of one drug to a stable long-term regimen of the other has resulted in myopathy and rhabdomyolysis (including a fatality) Weigh the potential benefits and risks and carefully monitor patients for any signs or symptoms of muscle pain, tenderness, or weakness, particularly during initial therapy; monitoring CPK...
Fluvastatin · 5 minor + 12 total pairs
- Glecaprevir/Pibrentasvir minor
- Sofosbuvir/Velpatasvir minor
- Terbinafine minor
- Warfarin minor
Colchicine · 4 major-labeled pairs (vs Fluvastatin's 1)
- Azithromycin minor
- Cyclosporine minor
- Digoxin minor
- Diltiazem minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
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