colchicine vs fluvastatin
PlainMeds reviewed this comparison against our methodology in August 2026. It places FDA and CMS record fields side by side, without recommending either medication.
Side-by-side comparison of colchicine and fluvastatin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Other Potentially Significant Drug Interactions Concomitant Drug Class or Food Noted or Anticipated Outcome Clinical Comment HMG-CoA Reductase Inhibitors: atorvastatin, fluvastatin, lovastatin, pravastatin, simvastatin Pharmacokinetic and/or pharmacodynamic interaction: the addition of one drug to a stable long-term regimen of the other has resulted in myopathy and rhabdomyolysis (including a fatality) Weigh the potential benefits and risks and carefully monitor patients for any signs or symptoms of muscle pain, tenderness, or weakness, particularly during initial therapy; monitoring CPK...
Colcrys, Mitigare
Lescol
Colchicine is a medicine used to prevent or treat gout flares and Familial Mediterranean Fever (FMF). It works by reducing inflammation and pain.
Fluvastatin (Lescol) is a medicine that helps lower cholesterol levels in your blood. It belongs to a group of drugs called statins.
Colchicine is used to prevent and treat gout flares in adults. Gout flares cause sudden, severe pain, redness, and swelling in your joints. Colchicine is also used to treat Familial Mediterranean Fever (FMF) in adults and children ages 4 and older. FMF causes recurring fevers and pain in the abdomen, chest, or joints.
This medicine is used to lower high cholesterol and triglycerides (fats) in adults and children (10-16 years old) with certain inherited cholesterol problems. It can also lower the risk of needing procedures to improve blood flow to the heart in adults with heart disease. Fluvastatin can also slow down the hardening of arteries in people with heart disease.
Colchicine reduces inflammation in the body. It does this by blocking certain processes that cause swelling and pain. This helps to relieve gout flares and manage FMF symptoms.
Fluvastatin works by blocking a substance your body needs to make cholesterol. This helps to lower bad cholesterol (LDL) and triglycerides while raising good cholesterol (HDL). By lowering cholesterol, it helps prevent heart disease and stroke.
- • Diarrhea
- • Abdominal pain
- • Nausea
- • Vomiting
- • Headache
- • Upset stomach
- • Muscle pain
- • Abdominal pain
- • Nausea
- Diarrhoea 2,660
- Nausea 1,940
- Fatigue 1,747
- Dyspnoea 1,467
- Acute Kidney Injury 1,436
- Myalgia 669
- Diarrhoea 371
- Dizziness 361
- Dyspnoea 340
- Nausea 337
Taking too much colchicine can be fatal in both adults and children. Keep this medicine out of the reach of children. Colchicine can also cause serious blood problems and muscle weakness. Certain medicines can interact with colchicine and cause life-threatening problems. Talk to your doctor about all the medicines you take.
This medicine can sometimes cause muscle problems, including rhabdomyolysis (a serious muscle breakdown that can lead to kidney damage). Tell your doctor right away if you have unexplained muscle pain, tenderness, or weakness, especially if you also have a fever or feel sick. This medicine can also cause liver problems. Your doctor should do blood tests to check your liver before you start taking fluvastatin and while you are taking it.
Tell your doctor if you are pregnant or plan to become pregnant. Colchicine may harm your unborn baby. It is not known if colchicine passes into breast milk. Talk to your doctor about the risks and benefits of taking colchicine while breastfeeding.
You should not take fluvastatin if you are pregnant or breastfeeding. This medicine can harm an unborn baby. If you are a woman who could become pregnant, use effective birth control while taking fluvastatin.
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How to Read This colchicine vs fluvastatin Comparison
colchicine is classified in the Anti-Gout Agent drug class, while fluvastatin sits within the HMG-CoA Reductase Inhibitor (Statin) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, colchicine has 9,250 submissions while fluvastatin has 2,078. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to combining these medications can cause muscle damage or weakness because both drugs can affect muscle health.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for colchicine or fluvastatin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.