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What the FDA labels say about taking them together

Flutamide and warfarin

Flutamide's FDA label of February 4, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name flutamide. The flutamide label: “Drug Interactions Increases in prothrombin time have been noted in patients receiving long-term warfarin therapy after Eulexin ® was initiated.”

Check it at the source: the flutamide FDA label on DailyMed (effective February 4, 2025, Waylis Therapeutics LLC); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the flutamide label say about warfarin?

Flutamide label, drug interactions

Drug Interactions Increases in prothrombin time have been noted in patients receiving long-term warfarin therapy after Eulexin ® was initiated.

Source: FDA drug label (Eulexin), Waylis Therapeutics LLC, effective February 4, 2025 (SPL set 0a905e25-42b6-4937-a689-f01a8f22e644), via openFDA; the full label on DailyMed

What does the warfarin label say about flutamide?

Warfarin's label (effective May 29, 2026) does not name flutamide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Flutamide generic labelers
19Warfarin generic labelers
FlutamideWarfarin
Labeled forn/aBlood clots (DVT and PE), Atrial fibrillation
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?