Fluconazole · more major-labeled pairs than Amphotericin B
SPL labels Fluconazole + Amphotericin B as minor; Fluconazole 57 / Amphotericin B 9 in that band.
Mechanism on file: These two drugs can sometimes work against each other depending on the type of fungus being treated. This means they might be less effective when used together than when used alone.
FDA SPL severity: Minor
Fluconazole + Amphotericin B · SPL mechanism field
These two drugs can sometimes work against each other depending on the type of fungus being treated. This means they might be less effective when used together than when used alone.
Minor band excerpt · Fluconazole with Amphotericin B
Amphotericin B : Concurrent administration of fluconazole and amphotericin B in infected normal and immunosuppressed mice showed the following results: a small additive antifungal effect in systemic infection with Candida albicans , no interaction in intracranial infection with Cryptococcus neoformans , and antagonism of the two drugs in systemic infection with A.
Fluconazole · 3 major-labeled pairs (vs Amphotericin B's 1)
- Amitriptyline minor
- Amlodipine minor
- Azithromycin minor
- Carvedilol minor
Amphotericin B · 9 minor + 12 total pairs
- Anidulafungin minor
- Dexamethasone minor
- Dronabinol minor
- Fludrocortisone minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.