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What the FDA labels say about taking them together

Felodipine and paclitaxel

Paclitaxel's FDA label of January 21, 2026 names felodipine in its drug interactions section; the felodipine label PlainMeds reads does not name paclitaxel.

Check it at the source: the felodipine FDA label on DailyMed (effective August 11, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the paclitaxel FDA label on DailyMed (effective January 21, 2026, Natco Pharma USA LLC).

What does the felodipine label say about paclitaxel?

Felodipine's label (effective August 11, 2026) does not name paclitaxel in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (FELODIPINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective August 11, 2026 (SPL set 0bef7cf2-012b-4804-ac93-0a8b333035db), via openFDA; the full label on DailyMed

What does the paclitaxel label say about felodipine?

Paclitaxel label, drug interactions

Caution should be exercised when paclitaxel is concomitantly administered with known substrates (eg, midazolam, buspirone, felodipine, lovastatin, eletriptan, sildenafil, simvastatin, and triazolam), inhibitors (eg, atazanavir, clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin), and inducers (eg, rifampin and carbamazepine) of CYP3A4. ( See CLINICAL PHARMACOLOGY section. ) Caution should also be exercised when paclitaxel is concomitantly administered with known substrates (eg, repaglinide and rosiglitazone), inhibitors (eg, gemfibrozil), and inducers (eg, rifampin) of CYP2C8. ( See CLINICAL PHARMACOLOGY. …

Source: FDA drug label (Paclitaxel), Natco Pharma USA LLC, effective January 21, 2026 (SPL set a1eb16b4-285b-4e81-9c4e-1244d4a52af8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Felodipine generic labelers
19Paclitaxel generic labelers
FelodipinePaclitaxel
Labeled forHigh blood pressureBreast cancer, Lung cancer
Boxed warningNoYes
Pharmacy cost (NADAC)$0.123 per tablet 5 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?