What the FDA labels say about taking them together
Felodipine and lopinavir/ritonavir
Lopinavir/ritonavir's FDA label of July 23, 2026 names felodipine in its drug interactions section; the felodipine label PlainMeds reads does not name lopinavir/ritonavir. The lopinavir/ritonavir label: “Clinical monitoring of patients is recommended and a dose reduction of the dihydropyridine calcium channel blocker may be considered.”
Check it at the source: the felodipine FDA label on DailyMed (effective August 11, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the lopinavir/ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the felodipine label say about lopinavir/ritonavir?
Felodipine's label (effective August 11, 2026) does not name lopinavir/ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (FELODIPINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective August 11, 2026 (SPL set 0bef7cf2-012b-4804-ac93-0a8b333035db), via openFDA; the full label on DailyMed
What does the lopinavir/ritonavir label say about felodipine?
Lopinavir/ritonavir label, drug interactionsConcomitant Drug Class/Drug Name: Dihydropyridine Calcium Channel Blockers: e.g. felodipine, nifedipine, nicardipine; Effect on Concentration of Lopinavir or Concomitant Drug: ↑ dihydropyridine calcium channel blockers; Clinical Comments: Clinical monitoring of patients is recommended and a dose reduction of the dihydropyridine calcium channel blocker may be considered.
Source: FDA drug label (Kaletra), AbbVie Inc., effective July 23, 2026 (SPL set 8290add3-4449-4e58-6c97-8fe1eec972e3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Felodipine | Lopinavir/ritonavir | |
|---|---|---|
| Labeled for | High blood pressure | HIV |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.123 per tablet 5 mg tablet | $4.46 per tablet 200-50 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once