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What the FDA labels say about taking them together

Felodipine and fosamprenavir

Fosamprenavir's FDA label of September 15, 2023 names felodipine in its drug interactions section; the felodipine label PlainMeds reads does not name fosamprenavir. The fosamprenavir label: “Use with caution. Clinical monitoring of patients is recommended.”

Check it at the source: the felodipine FDA label on DailyMed (effective August 11, 2026, Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.); the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.).

What does the felodipine label say about fosamprenavir?

Felodipine's label (effective August 11, 2026) does not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (FELODIPINE), Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., effective August 11, 2026 (SPL set 0bef7cf2-012b-4804-ac93-0a8b333035db), via openFDA; the full label on DailyMed

What does the fosamprenavir label say about felodipine?

Fosamprenavir label, drug interactions

Concomitant Drug Class/Drug Name: Calcium channel blockers: Diltiazem, felodipine, nifedipine, nicardipine, nimodipine, verapamil, amlodipine, nisoldipine, isradipine; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Calcium channel blockers; Clinical Comment: Use with caution. Clinical monitoring of patients is recommended.

Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Felodipine generic labelers
2Fosamprenavir generic labelers
FelodipineFosamprenavir
Labeled forHigh blood pressureHIV
Boxed warningNoNo
Pharmacy cost (NADAC)$0.123 per tablet 5 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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