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What the FDA labels say about taking them together

Carbamazepine and exemestane

Exemestane's FDA label of September 12, 2024 names carbamazepine in its drug interactions section; the carbamazepine labels PlainMeds reads (3) do not name exemestane. The exemestane label: “Drugs That Induce CYP 3A4 Co-medications that induce CYP 3A4 may significantly decrease exposure to exemestane.”

Check it at the source: the carbamazepine FDA label on DailyMed (effective August 20, 2026, Novartis Pharmaceuticals Corporation); the exemestane FDA label on DailyMed (effective September 12, 2024, Breckenridge Pharmaceutical, Inc.).

What does the carbamazepine label say about exemestane?

Carbamazepine's label (effective August 20, 2026) and its 2 other brand-application labels do not name exemestane in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Tegretol), Novartis Pharmaceuticals Corporation, effective August 20, 2026 (SPL set 8d409411-aa9f-4f3a-a52c-fbcb0c3ec053), via openFDA; the full label on DailyMed

What does the exemestane label say about carbamazepine?

Exemestane label, drug interactions

Drugs That Induce CYP 3A4 Co-medications that induce CYP 3A4 (e.g., rifampicin, phenytoin, carbamazepine, phenobarbital, or St. John's Wort) may significantly decrease exposure to exemestane.

Source: FDA drug label (Exemestane), Breckenridge Pharmaceutical, Inc., effective September 12, 2024 (SPL set 4e3fd382-19f5-4ded-ab22-39d5b1b2f366), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

42Carbamazepine generic labelers
10Exemestane generic labelers
CarbamazepineExemestane
Labeled forBipolar disorder, Seizures and epilepsyBreast cancer
Boxed warningYesNo
Pharmacy cost (NADAC)$0.119 per tablet 200 mg tablet$0.748 per tablet 25 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?